Please Note: Patients with Inhibitors require Special Treatment
- Aspirin impairs platelet function which may compound an existing bleeding disorder.
(see package insert)
- Antifibrinolytic – prevents clot breakdown.
- Indicated for mucous membrane bleeding.
- Contraindicated in haematuria or with concurrent use of Factor IX complex, or activated PCC.
- Moderate or mild haemophilia A and von Willebrand disease.
- Releases stored Factor VIII and vWF into circulation.
- Less effective with lower baseline Factor VIII level.
- Tachyphylaxis may occur with repeat doses.
NB:
- Beware of fluid retention and syndrome of inappropriate ADH secretion
- Monitor weight and baseline U+E
- Restrict fluid as necessary
Press on area > 5 min.
Apply ice.
Subcutaneous injection is safer.
- Avoid other intramuscular injections in Haemophilia.